Malaria is a life-threatening disease caused by parasites. It is transmitted to humans through the bites of infected female mosquitoes. Malaria can be found in most tropical and subtropical climates. But Africa is the most affected for a number of reasons. In 2021, 619,000 people died of malaria worldwide. Most were young children in sub-Saharan Africa. However, there is hope. Two recently-approved vaccines may provide some protection against this deadly disease.